CLINICAL MANIFESTATIONS OF CANINE LEISHMANIOSIS

Clinical manifestations and laboratory abnormalities found in CanL due to L. infantum

CLINICAL MANIFESTATIONS LABORATORY ABNORMALITIES
General
Generalized lymphadenomegaly
Loss of body weight
Decreased or increased appetite
Lethargy
Mucous membranes pallor
Splenomegaly
Polyuria and polydipsia
Fever
Vomiting
Diarrhea

Cutaneous
Non-pruritic exfoliative dermatitis with or without alopecia
Erosive-ulcerative dermatitis
Nodular dermatitis
Papular dermatitis
Pustular dermatitis
Onychogryphosis

Ocular
Blepharitis (exfoliative, ulcerative or nodular) and conjunctivitis (nodular)
Keratoconjunctivitis, either common or sicca
Anterior uveitis
Endophtalmitis

Other
Mucocutaneous and mucosal ulcerative or nodular lesions (oral, genital and nasal)
Epistaxis
Lameness (erosive or non-erosive polyarthritis, osteomyelitis and polymyositis)
Atrophic masticatory myositis
Vascular disorders (systemic vasculitis and arterial thromboembolism)
Neurological disorders

CBC*/Hemostasis
Mild to moderate non-regenerative anemia
Leukocytosis or leukopenia: lymphopenia, neutrophilia, neutropenia
Thrombocytopathy
Thrombocytopenia
Impaired secondary hemostasis and fibrinolysis

Serum biochemical profile with proteins electrophoresis
Hyperproteinemia
Hyperglobulinemia (polyclonal beta and/or gammaglobulinemia)
Hypoalbuminemia
Decreased albumin/globulin ratio
Renal azotemia
Elevated liver enzyme activities
Proteinuria

* CBC: complete blood count

 

Ulcerocrusted papulo-nodular dermatitis (“inoculation sore”)

Periorbital alopecia and exfoliative facial dermatitis
 

Periorbital alopecia and nasal hyperkeratosis

Exfoliative dermatitis
 

Mucocutaneous ulcerative lesions and Vasculitis

Keratouveitis
 
Pictures: © Guadalupe Miró