Canine Leishmaniosis

Etiology, Distribution & Transmission
Canine Leishmania infections are predominantly due to Leishmania infantum. However, other zoonotic species of Leishmania may infect dogs. The information in these…
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Canine Leishmaniosis

Clinical signs

Clinical
Manifestations

Main clinical signs and laboratory abnormalities found in CanL due to L. infantum. General: Generalized lymphadenomegaly, loss of body weight, decreased or increased appetite…
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Diagnostic approach

Diagnosis
 

Diagnosis is based on clinical signs and/or clinicopathological abnormalities compatible with disease combined with confirmation of L. infantum infection, predominantly…
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Clinical staging

Treatment and
Prognosis

Staging is performed following canine patient diagnosis of L. infantum infection with clinical signs and/or clinicopathologic abnormalities to facilitate appropriate…
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Treatment protocols

Therapy
 

Current treatment protocols for CanL.
Meglumine antimoniate, Miltefosine, Allopurinol, Domperidone and Dietary nucleotides with AHCCc…
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Monitoring
 

Recommended monitoring during and after treatment of CanL.
Parameters and frequency. Clinical history and physical examination…
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Prevention
Prevention for individual dogs should always include use of a topical insecticide maintained throughout the period of sand flies activity.
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Vaccines
A first vaccine based on adjuvanted purified excreted/secreted antigens of L. infantum was initially licensed in Europe in 2011.
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