Faculty of Veterinary Medicine
University of Naples “Federico II”
Via F. Delpino, 1, 80137 Naples – Italy
Faculty of Veterinary Medicine, Naples University.
Prof. Oliva graduated from the Naples Faculty of Veterinary Medicine in Italy in 1984. He did a Small Animal internship at the Naples University from 1984 to 1987 followed by a permanent position in the same Faculty as Graduate Technician. He did a three months fellowship in Endocrinology at the Department of Clinical Sciences of Companion Animals, University of Utrecht – The Netherlands.
Prof. Oliva’s research interests focus on the pathogenesis, diagnosis, prevention and treatment of veterinary and zoonotic vector-borne infectious diseases, with particular interest in Canine Leishmaniasis. He is a member of the LeishVet group for standardization of the diagnosis, treatment and prevention of canine leishmanioasis, and member of the Italian SCIVAC group for studying canine leishmaniasis (CLWG).
Prof. Oliva heads the Department of Veterinary Clinical Sciences at Veterinary Faculty of Naples, Italy. The department research is funded by several international and national funding received from institutional and private partners: Italian Ministry of Health; Italian Ministry of University and Research; Istituto Superiore di Sanità, Rome; Campania (Italy) Region; Istituto Zooprofilattico of Naples; Istituto Zooprofilattico of Palermo (CRENAL center); different national and international Universities; several private drug’s and diagnostic companies.
He has extensive research collaborations with the Istituto Superiore di Sanità, Rome, Italy, in particular with the “Reparto di Malattie trasmesse da Vettori e Sanità Internazionale Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate” (MIPI), in developping vaccines against canine and human Leishmaniasis.
Participation to ISS/Infectious Disease Research Institute (Seattle, USA) Project “Therapeutic efficacy of Leishmania recombinant antigens in dogs naturally infected by Leishmania infantum” (2000–2003).
Dep Vet Clin Sci Naples/ ISS/ Private companies Animal Health Project “Efficacy testing of Leishmania vaccines in dogs under field conditions in Italy” (2005-present). The research activities have been mainly addressed to the study and control of leishmaniasis entities endemic in the Mediterranean and Middle East countries. They include both human and animal forms of the diseases in the fields of parasite taxonomy, diagnostics, therapy, emidemiological surveillance, control methods and vaccines.
Oliva G, Gradoni L, Ciaramella P, De Luna R, Cortese L, Orsini S, Davidson RN, Persechino A. Activity of liposomal amphotericin B (AmBisome) in dogs naturally infected with Leishmania infantum.J Antimicrob Chemother. 1995 Dec;36 (6):1013-9.
Ciaramella P, Oliva G, Luna RD, Gradoni L, Ambrosio R, Cortese L, Scalone A, Persechino A. A retrospective clinical study of canine leishmaniasis in 150 dogs naturally infected by Leishmania infantum. Vet Rec. 1997 Nov 22;141(21):539-43.
Oliva G, Gradoni L, Cortese L, Orsini S, Ciaramella P, Scalone A, de Luna R, Persechino A. Comparative efficacy of meglumine antimoniate and aminosidine sulphate, alone or in combination, in canine leishmaniasis. Ann Trop Med Parasitol. 1998 Mar;92(2):165-71.
Scalone A, De Luna R, Oliva G, Baldi L, Satta G, Vesco G, Mignone W, Turilli C, Mondesire RR, Simpson D, Donoghue AR, Frank GR, Gradoni L. Evaluation of the Leishmania recombinant K39 antigen as a diagnostic marker for canine leishmaniasis and validation of a standardized enzyme-linked immunosorbent assay. Vet Parasitol. 2002 Apr 2;104(4):275-85.
Gradoni L, Foglia Manzillo V, Pagano A, Piantedosi D, De Luna R, Gramiccia M, Scalone A, Di Muccio T, Oliva G. Failure of a multi-subunit recombinant leishmanial vaccine (MML) to protect dogs from Leishmania infantum infection and to prevent disease progression in infected animals. Vaccine. 2005 Nov 1;23(45):5245-51. Epub 2005 Jul 18.
Oliva G, Scalone A, Foglia Manzillo V, Gramiccia M, Pagano A, Di Muccio T, Gradoni L. Incidence and time course of Leishmania infantum infections examined by parasitological, serologic, and nested-PCR techniques in a cohort of naive dogs exposed to three consecutive transmission seasons. J Clin Microbiol. 2006 Apr;44(4):1318-22.
Foglia Manzillo V, Oliva G, Pagano A, Manna L, Maroli M, Gradoni L. Deltamethrin-impregnated collars for the control of canine leishmaniasis: evaluation of the protective effect and influence on the clinical outcome of Leishmania infection in kennelled stray dogs. Vet Parasitol. 2006 Nov 30;142(1-2):142-5. Epub 2006 Aug 1.
Paciello O, Oliva G, Gradoni L, Manna L, Manzillo VF, Wojcik S, Trapani F, Papparella S. Canine inflammatory myopathy associated with Leishmania Infantum infection. Neuromuscul Disord. 2009 Feb;19(2):124-30. Epub 2008 Dec 11.
Solano-Gallego L, Koutinas A, Miró G, Cardoso L, Pennisi MG, Ferrer L, Bourdeau P, Oliva G, Baneth G. Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis. Vet Parasitol. 2009 Oct 28;165(1-2):1-18.
Oliva G, Roura X, Crotti A, Maroli M, Castagnaro M, Gradoni L, Lubas G, Paltrinieri S, Zatelli A, Zini E. Guidelines for treatment of leishmaniasis in dogs. J Am Vet Med Assoc. 2010 Jun 1;236(11):1192-8.
Gramiccia M, Di Muccio T, Fiorentino E, Scalone A, Bongiorno G, Cappiello S, Paparcone R, Foglia Manzillo V, Maroli M, Gradoni L, Oliva G. Longitudinal study on the detection of canine Leishmania infections by conjunctival swab analysis and correlation with entomological parameters. Vet Parasitol. 2010 Aug 4;171(3-4):223-8.
Maroli M, Gradoni L, Oliva G, Castagnaro M, Crotti A, Lubas G, Paltrinieri S, Roura X, Zini E, Zatelli A. Guidelines for prevention of leishmaniasis in dogs. J Am Vet Med Assoc. 2010 Jun 1;236(11):1200-6.
LeishVet guidelines for the practical management of canine leishmaniosis.
Solano-Gallego L, Miró G, Koutinas A, Cardoso L, Pennisi MG, Ferrer L, Bourdeau P, Oliva G, Baneth G, The LeishVet Group. Parasit Vectors. 2011 May 20;4:86.
Aslan H, Dey R, Meneses C, Castrovinci P, Jeronimo SM, Oliva G, Fischer L, Duncan RC, Nakhasi HL, Valenzuela JG, Kamhawi S. A new model of progressive visceral leishmaniasis in hamsters by natural transmission via bites of vector sand flies. J Infect Dis. 2013 Apr 15;207(8):1328-38.
Foglia Manzillo V, Di Muccio T, Cappiello S, Scalone A, Paparcone R, Fiorentino E, Gizzarelli M, Gramiccia M, Gradoni L, Oliva G. Prospective study on the incidence and progression of clinical signs in naïve dogs naturally infected by Leishmania infantum. PLoS Negl Trop Dis. 2013 May 9;7(5):e2225.
Roura X, Fondati A, Lubas G, Gradoni L, Maroli M, Oliva G, Paltrinieri S, Zatelli A, Zini E. Prognosis and monitoring of leishmaniasis in dogs: a working group report Vet J. 2013 Oct;198(1):43-7.
Bongiorno G, Paparcone R, Foglia Manzillo V, Oliva G, Cuisinier AM, Gradoni L. Vaccination with LiESP/QA-21 (CaniLeish®) reduces the intensity of infection in Phlebotomus perniciosus fed on Leishmania infantum infected dogs–a preliminary xenodiagnosis study. Vet Parasitol. 2013 Nov 8;197(3-4):691-5.
Bourdeau P, Saridomichelakis MN, Oliveira A, Oliva G, Kotnik T, Gálvez R, Foglia Manzillo V, Koutinas AF, Pereira da Fonseca I, Miró G. Management of canine leishmaniosis in endemic SW European regions: a questionnaire-based multinational survey. Parasit Vectors. 2014 Mar 24;7:110.
Dantas-Torres F, Baneth G, Miró G, Cardoso L, Oliva G, Solano-Gallego L, Bourdeau P, Otranto D. Further thoughts on “Asymptomatic dogs are highly competent to transmit Leishmania (Leishmania) infantum chagasi to the natural vector”. Vet Parasitol. 2014 Aug 29;204(3-4):443-4.
Oliva G, Nieto J, Foglia Manzillo V, Cappiello S, Fiorentino E, Di Muccio T, Scalone A, Moreno J, Chicharro C, Carrillo E, Butaud T, Guegand L, Martin V, Cuisinier AM, McGahie D, Gueguen S, Cañavate C, Gradoni L. A randomised, double-blind, controlled efficacy trial of the LiESP/QA-21 vaccine in naïve dogs exposed to two leishmania infantum transmission seasons. PLoS Negl Trop Dis. 2014 Oct 9;8(10):e3213.
Kostalova T, Lestinova T, Sumova P, Vlkova M, Rohousova I, Berriatua E, Oliva G, Fiorentino E, Scalone A, Gramiccia M, Gradoni L, Volf P. Canine Antibodies against Salivary Recombinant Proteins of Phlebotomus perniciosus: A Longitudinal Study in an Endemic Focus of Canine Leishmaniasis. PLoS Negl Trop Dis. 2015 Jun 25;9(6):e0003855.